insulinsecretion相关论文
目的:观察小干扰RNA(small interfering RNA,siRNA)干扰囊泡膜核苷酸转运体(vesicular nucleotide transporter,VNUT)基因对大鼠胰腺β细......
Effect of Compound K on enhancing insulin secretion in MIN6 pancreatic β-cells by upregulation of GL
Aim: Compound K (CK) is a final intestinal metabolite of protopanaxadiol-type ginsenosides from Panax ginseng and shows ......
TRPA1 mediates restoration of insulin secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypas
Roux-en-Y gastric bypass(RYGB)is an effective procedure for the treatment of type 2 diabetes(T2D).The mechanism of impro......
SIRT5 protects pancreatic beta cell from glycolipotoxicity-induced apoptosis via interaction with Bc
Progressive beta cell apoptosis is a major cause leading to a decline in beta cell mass in type 2 diabetes.While it has ......
While molecular regulation of insulin granule exocytosis is relatively well understood,insulin granule biogenesis and ma......
A large body of evidence shows that activation of glucagon-like peptide 1 receptor (GLP-1R) signaling enhances β-cell f......
GENERATION OF TRANSGENIC MICE FOR IN VIVO DETECTION OF INSULIN-CONTAINING GRANULE EXOCYTOSIS AND QUA
Insulin secretion is a complex and highly regulated process. Although much progress has been made in understanding the c......
Regulation of leptin on insulin secretion and sulfonulurea receptor 1 transcription level in isolate
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Effects of supraphysiologic concentration glucose on pancreatic duodenal homeobox-1 expression and i
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miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pent
High fatty acid reduces insulin secretion in pancreatic β-cells and miR-139-5p is increased in dia-betic pancreatic tis......
目的探讨Resistin基因过表达对大鼠胰岛β细胞株RINm5F基础胰岛素分泌的影响。方法体外培养大鼠胰岛β细胞株RINm5F,采用PCR法扩增......
目的探讨胰腺脂肪浸润对营养性肥胖大鼠的胰岛功能及形态影响。方法刚断乳SD雄性大鼠70只,随机分为普通饲料组(N组)和高脂饲料组(F......
Anti-diabetic effects of Caulerpa lentillifera:stimulation of insulin secretion in pancreatic β-cell
Objective:To evaluate anti-diabetic effect of Caulrpa kntillifera(C.lentillifera).Methods:The inhibitory effect of C.len......